Journal of Liver Cancer

Dong Gu Kim

2 Articles

Rapid recurrence following living donor liver transplantation for hepatocellular carcinoma within Milan criteria: Hyun Young Woo, Jin Dong Kim, Jung Hyun Kwon, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Sung Eun Rha, Jae Young Byun, Ho Jong Chun, Byung Gil Choi, Hae Kyu Lee, Young Kyoung You, Dong Gu Kim; Journal of the Korean Liver Cancer Study Group. 2009;9(1):45-48. Published online June 30, 2009

Abstract PDF: Liver transplantation is curative therapy for hepatocellular carcinoma especially if ,within Milan criteria, 4 year survival and recurrence-free survival was reported to be 85% and 92%, respectively. Herein we report a patient who experience rapid recurrence following living donor liver transplantation (LDLT) for hepatocellular carcinoma within Milan criteria. A 52 year-old-men patient with known liver cirrhosis associated with hepatitis B virus was admitted for the treatment of hepatocellular carcinoma (HCC). Abdominal CT revealed two nodules less than 3 cm in right hepatic lobe. After single session of transcatheter arterial chemoembolization (TACE), the patient underwent LDLT. After seven months following transplantation, recurrent HCC was detected on transplanted liver with concurrent metastatic nodule in lung. Although TACE and metastsectomy were performed for recurrent intrahepatic mass and lung metastasis, recurrent HCC showed rapid progression and patient died of progressive tumor after 10 months following LDLT.

A Case of Advanced Hepatocellular Carcinoma : Curative Resection after Repeated Transcatheter Arterial Chemoembolization, Systemic Chemotherapy and Radiotherapy: So Yeon Lee, Seung Kew Yoon, Min Su Kim, Si Hyun Bae, Jong Young Choi, Byung Gil Choi, Ho Jong Chun, Dong Gu Kim, Seok Whan Moon; Journal of the Korean Liver Cancer Study Group. 2006;6(1):38-41. Published online June 30, 2006

Abstract PDF: A 46 year-old male patient was admitted to our hospital for evaluation of hepatic mass which was detected on ultrasonography. He had a history of chronic hepatitis B carrier. Laboratory findings showed that HBsAg was positive, and HBeAg was negative. AFP was 2,081.1 ng/mL. Abdomen CT showed a large well-defined low density lesion involving entire right hepatic lobe which was compatable with advanced hepatocellular carcinoma (stage III). Celiac and hepatic arteriogram reveled huge hypervascular mass at both lobe of the liver. Transcatheter arterial chemoembolization (TACE), systemic chemotherapy, percutaneous ethanol injection therapy (PEIT), and radiotherapy were combined as the treatment of huge hepatoma. After combined therapy, tumor decreased in size. As a result, curative right lobectomy could be performed. Six months after surgery, chest CT showed two small metastatic nodules in both lung, so wedge resection was performed. We followed the patient for 5 years after operation and there was no evidence of regional tumor recurrence or distant metastasis.